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First-line protocols prioritize intravenous tissue plasminogen activator (Zhao et al., 2022) supplemented by dual antiplatelet therapy (aspirin/clopidogrel) for minor strokes, while mechanical thrombectomy is reserved as the gold-standard intervention for disabling cases (Mendelson and Prabhakaran, 2021)

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2003 May 1;371(Pt 3):887-95